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Trends and needs in photobiomodulation therapy
PRAVEEN ARANY, DDS, Ph.D., Assistant Professor, Oral Biology & Biomedical Engineering,
School of Dental Medicine, Engineering & Applied Sciences, University at Buffalo
Will low-intensity laser light have a medical impact? While the experienced laser user may strongly doubt that, this presentation delivered good reason to believe that the effect is not only proven in
clinical tests, but there are also scientific explanations of when and why it works.
First, it is specific light with a specified range of
wavelengths and specific intensities that works in
this field of photobiomodulation (PBM). Even in
the early days of lasers, it was found that certain
nondestructive and even nonthermal effects may
influence wound healing or hair growth.
In the meantime, more than a dozen applica-
tions of PBM have been identified. From our per-
sonal perspectives, we know that a reasonable
dose of sunlight is good for health. In clinical
terms, light has been tested for treatment in a
similar fashion as any other drug. There is even
a name for such medication: photoceuticals. This
light has an influence on biological processes, just
as pharmaceuticals have. And similarly, proper
light parameters strongly depend on the biolog-
ical process to be controlled. As with any drug,
the new PBM procedures must be tested for ther-
apeutic thresholds and phototoxicity.
Praveen Arany from the University at Buffalo
showed some examples of typical PBM mechanisms, where specific light triggers specific reactions on a sub-cellular level, which, for example,
can be connected to anti-inflammatory effects.